Lipids boost the brain
Consuming oils with high polyunsaturated fatty acid content, in particular those containing omega-3s, is beneficial for the health. But the mechanisms underlying this phenomenon are poorly known....
View ArticleTeam identifies important regulators of immune cell response
In a collaborative study, scientists from the Florida campus of The Scripps Research Institute (TSRI) and the La Jolla Institute for Allergy and Immunology have developed a more effective method to...
View ArticleTurmeric compound boosts regeneration of brain stem cells
A bioactive compound found in turmeric promotes stem cell proliferation and differentiation in the brain, reveals new research published today in the open access journal Stem Cell Research &...
View ArticleReprogrammed cells grow into new blood vessels
By transforming human scar cells into blood vessel cells, scientists at Houston Methodist may have discovered a new way to repair damaged tissue. The method, described in an upcoming issue of...
View ArticleResearchers unlock protein key to harnessing regenerative power of blood stem...
(Medical Xpress)—UCLA scientists have for the first time identified a protein that plays a key role in regulating how blood stem cells replicate in humans.
View ArticleNew strategic approach against bowel cancer
Colorectal carcinoma is the most frequent type of bowel cancer and the second most common tumour disease among men and women in Germany. So-called microsatellite stable colorectal cancer with mutations...
View ArticleHow an FDA-approved drug boosts myelin synthesis
Damage to myelin, the fatty insulator that enables communication between nerve cells, characterizes multiple sclerosis (MS) and other devastating neurological diseases.
View ArticleScientists produce hypothalamic neurons, which can help target a range of...
Collaborating with scientists from New York, Toronto, and Tokyo, Harvard Stem Cell Institute (HSCI) researchers have devised two methods for using stem cells to generate the type of neurons that help...
View ArticleReview article provides new insights on how tumors metastasize
In a review article recently published in the journal Clinical and Translational Medicine, researchers from Boston University School of Medicine (BUSM) shed new light on the underlying processes of...
View ArticleA family found to have a self-healing skin cancer offers hope for better...
Members of a Tunisian family with tumors on their hands, feet and eyes may provide helpful information for the treatment of squamous cell carcinoma, a common skin cancer.
View ArticleTeam succeeds in producing photoreceptors from human embryonic stem cells
Age-related macular degeneration (AMRD) could be treated by transplanting photoreceptors produced by the directed differentiation of stem cells, thanks to findings published today by Professor Gilbert...
View ArticleManipulating the antennae on cells promises new treatments for osteoarthritis
Bioengineers from Queen Mary University of London (QMUL) have shown for the first time that lithium chloride, a common drug used to treat mental health disorders, could offer an effective treatment...
View ArticleNew mathematical models describe diffusion and metabolism dynamics in 3D...
New research has shed light on the complex interactions of stem cell function and molecular diffusion in neural tissue, which may explain many phenomena from stem cell differentiation to the formation...
View ArticleBlocking PRMT5 might force resistant brain-tumor cells into senescence, study...
A new study suggests that blocking an enzyme called PRMT5 in tumor cells could be a promising new strategy for the treatment of glioblastoma (GB), the most aggressive and lethal form of brain cancer.
View ArticleResearchers use a single molecule to command stem cells to build new bone
Researchers at the University of California San Diego have discovered an easy and efficient way to coax human pluripotent stem cells to regenerate bone tissue—by feeding them adenosine, a naturally...
View ArticleA stem cell gene found to command skeletal muscle regeneration
Prox1 gene has long been known to play an important role in fetal development. Finnish researchers have now discovered that Prox1 is essential also for skeletal muscle stem cell differentiation.
View ArticleStudy reveals new information on how brain cancer spreads
Glioblastoma multiforme remains the most common and highly lethal brain cancer and is known for its ability to relapse. Researchers at The University of Texas MD Anderson Cancer Center have identified...
View ArticleGene key for chemically reprogramming human stem cells
Scientists have discovered the gene essential for chemically reprogramming human amniotic stem cells into a more versatile state similar to embryonic stem cells, in research led by UCL and Heinrich...
View ArticleTumor suppressor promotes some acute myeloid leukemias, study reveals
Researchers in Germany have discovered that a tumor suppressor protein thought to prevent acute myeloid leukemia (AML) can actually promote a particularly deadly form of the disease. The study, "RUNX1...
View ArticleResearchers explore a potential therapeutic approach against cancer stem cells
Many cancer patients that receive chemotherapy go into remission at first, but relapse after treatment is discontinued. There is increasing evidence that this is due to the presence of cancer stem...
View ArticleSpherical biodegradable carriers support scalable and cost-effective stem...
Bone tissue engineering is theoretically now possible at a large scale. A*STAR researchers have developed small biodegradable and biocompatible supports that aid stem cell differentiation and...
View ArticleEpigenetic program leading to vessel differentiation
Clarification of how human blood vessels are constructed is desperately needed to advance regenerative medicine. A collaborative research group from Kumamoto University, Kyoto University, and the...
View ArticleCancer therapy shows promise for psoriasis treatment
HDAC inhibitors, already widely used to treat cancer, may be an effective therapy for psoriasis as well, scientists report.
View ArticleResearchers show how a protein prevents the uncontrolled expansion of immune...
The mammalian immune system consists of millions of individual cells that are produced daily from precursor cells in the bone marrow. During their development, immune cells undergo a rapid expansion,...
View ArticleStudy suggests epilepsy drug can be used to treat form of dwarfism
A drug used to treat conditions such as epilepsy has been shown in lab tests at The University of Manchester to significantly improve bone growth impaired by a form of dwarfism.
View ArticleScientists pinpoint surprising origin of melanoma
Led by Jean-Christophe Marine (VIB-KU Leuven), a team of researchers has tracked down the cellular origin of cutaneous melanoma, the deadliest form of skin cancer. The team was surprised to observe...
View ArticleThree-dimensional folding of DNA provides important epigenetic mechanisms in...
During differentiation of pluripotent stem cells to cardiomyocytes, the three-dimensional folding of the DNA reorganizes itself. This reorganization of the DNA architecture precedes and defines...
View ArticleA repurposed drug could open door to more stem cell transplants
A medication used to treat joint and skin conditions might also help people whose only hope of surviving cancer is receiving stem cells from a donor, according to research by a University of British...
View ArticleNew molecular probes to allow non-destructive analysis of bioengineered...
A new study describes novel probes that enable non-invasive, non-destructive, direct monitoring of the differentiation of mesenchymal stem cells (MSCs) in real-time during the formation of engineered...
View ArticleHedgehog signaling proteins keep cancer stem cells alive
Researchers from Charité - Universitätsmedizin Berlin have discovered that the survival of cancer stem cells is dependent on the Hedgehog signaling pathway. Targeting this pathway had previously shown...
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